
DSIP
A peptide studied for slow-wave sleep (delta waves).
iThe essentials in 10 seconds
- Deep sleep peptide (delta waves), discovered in the brain
- Promotes falling asleep and more restorative sleep
- Modulates stress and the nervous system
- Via injection pen (subcutaneous), in the evening
IWhat is DSIP?
DSIP (Delta Sleep-Inducing Peptide) is a small peptide naturally present in the brain, involved in triggering deep sleep (delta wave sleep). It promotes falling asleep, sleep quality, and modulates the stress response. It is a lead for sleep disorders, often as a complement to sleep hygiene.
An older peptide with limited and heterogeneous human data. Supervised use recommended; to be combined with good sleep hygiene.
The molecules presented on this site are innovative and fall under experimental use. Human data remain limited: a studied mechanism or a preclinical observation is not sufficient to demonstrate a benefit. The regulatory status in Morocco is not established for most of these peptides. Any use is decided within the framework of a medical consultation, with follow-up — never alone, never without an assessment.
IIThe benefits
Promotes the transition to sleep in the evening.
Supports delta wave sleep, the most restorative.
Modulates the stress response and promotes nighttime relaxation.
May help rebalance the rhythm when sleep is disrupted.
Better quality sleep affects energy and mood.
Deep sleep consolidates memory and mental clarity.
IIIRecommendations & how to use
Route: subcutaneous injection with the injection pen (abdomen) — fixed dose, regular technique and no dosing error · Timing: in the evening, about 30 to 60 min before bedtime · Storage: refrigerated (2–8 °C), 28 days after reconstitution
To be combined with good sleep hygiene.
| Dosage | Price |
|---|---|
| 10 mg | Provided on request |
Prices are not published online: they are provided on request, during a consultation or by telephone.

IVThe two protocols
Goal: improve falling asleep and sleep quality.
Monitoring: time to fall asleep, sleep quality, awakenings.
Goal: support relaxation and recovery during periods of tension.
Sleep hygiene remains the foundation: DSIP is a complement.
VProtocol rules
- Regular bedtime
- Screens and bright light off in the evening
- Inject in the evening
- Note time to fall asleep and sleep quality
- Keep the cartridge in the refrigerator (2–8 °C)
- No use of the pen without medical training
- Caffeine / late stimulants: avoid in the evening
- Do not drive right after injection
- Do not chain courses without a break
- Pregnancy, breastfeeding: medical advice
VIYour journey in 3 steps
Sleep evaluation, contraindications, training, protocol provided.
Injections in the evening, monitoring of sleep quality.
Sleep review, decision on next steps and associated hygiene.
VIISide effects & level of evidence
- Drowsiness
- Headache
- Mild hypotension
- Vivid dreams, nausea
- Injection-site reaction
- Pregnancy, breastfeeding
- Severe hypotension
- Driving and machinery for hours afterwards
- Hypersensitivity
Non-exhaustive list based on the available literature and known class effects; it replaces neither a product label nor an individual medical assessment.
VIIIPublications & references
- Delta sleep-inducing peptidePollard BJ, Pomfrett CJ · Eur J Anaesthesiol · 2001 · PMID 11437870
- Delta-sleep-inducing peptide (DSIP): a reviewGraf MV, Kastin AJ · Neurosci Biobehav Rev · 1984 · PMID 6145137
- Delta sleep-inducing peptide (DSIP): a still unresolved riddleKovalzon VM, Strekalova TV · J Neurochem · 2006 · PMID 16539679
Documentary references: the existence of a publication establishes neither efficacy nor safety for personal use. The regulatory status in Morocco must be verified.