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Kisspeptin-10

hormonal protocol
Brain & wellbeing · Testosterone & fertility

The natural conductor of the reproductive axis (LH/FSH).

iThe essentials in 10 seconds

  • Natural conductor of the reproductive axis (brain → sex hormones)
  • Stimulates the release of LH and FSH — and therefore testosterone / ovulation
  • Via injection pen (subcutaneous), under strict hormonal monitoring
  • Also explored for fertility and desire

IWhat is Kisspeptin-10?

Kisspeptin-10The hormonal regulator

Kisspeptin-10 is a peptide produced by the brain that commands the release of GnRH, the signal that triggers the production of LH and FSH by the pituitary gland — and therefore of sex hormones (testosterone, estrogens). It sits at the very top of the hormonal chain, making it a tool for exploring and supporting the reproductive axis.

Peptide hormonal: any use must be supervised by a workup and medical monitoring (risk of axis imbalance). Contraindicated in case of hormone-dependent tumor.

An innovative approach, an experimental use

The molecules presented on this site are innovative and fall under experimental use. Human data remain limited: a studied mechanism or a preclinical observation is not sufficient to demonstrate a benefit. The regulatory status in Morocco is not established for most of these peptides. Any use is decided within the framework of a medical consultation, with follow-up — never alone, never without an assessment.

IIThe benefits

◆Hormonal axisThe upstream signal

Stimulates the natural cascade of the reproductive axis (brain → pituitary → gonads).

◆TestosteroneIn men

May support natural testosterone production by stimulating LH.

◆OvulationIn women

May trigger LH release — explored in fertility and ovulation induction.

◆LibidoDesire

The supported hormonal axis may affect libido and sexual function.

◆FertilityThe desire for a child

Avenue of medical exploration in fertility support.

◆DiagnosisExploration of the axis

Used to test the reproductive axis response in a specialized setting.

IIIRecommendations & how to use

How to useDosage · route · storage
Reconstitution: vial reconstituted with bacteriostatic water then placed in a pen cartridge (preparation provided during consultation)

Route: subcutaneous injection with the injection pen (abdomen) — fixed dose, regular technique and no dosing error · Storage: refrigerated (2–8 °C), 28 days after reconstitution
Treatment mandatorily supervised: hormonal workup before, during and after.

Prices on request
DosagePrice
5 mgProvided on request

Prices are not published online: they are provided on request, during a consultation or by telephone.

Supplied as a ready-to-use pen: fixed dose, one injection a day.
Supplied as a ready-to-use pen: fixed dose, one injection a day.

IVThe two protocols

◆Hormonal protocolMen · axis support

Objective: support natural sex hormone production according to the profile.

Dose: according to the initial workup
Frequency: individualized protocol (1×/day or pulsatile)
Duration: short, with hormonal monitoring

Monitoring: hormonal workup (LH, FSH, testosterone / estradiol), tolerance.

◆Fertility protocolWith the specialist

Objective: support the reproductive axis as part of a fertility approach.

Strictly medical protocol, in collaboration with a specialist
Close hormonal monitoring
Decision to continue based on response

Any fertility approach is conducted as a team with a specialist.

VProtocol rules

Good habits
  • Scrupulously comply with the hormonal workup
  • Sleep and stress management (axis regulators)
  • Note effects and tolerance
  • Keep the cartridge in the refrigerator (2–8 °C)
  • Combine with follow-up by the attending physician / specialist
To avoid / precautions
  • Never self-medicate: hormonal peptide
  • Do not exceed the dose or extend without monitoring
  • Do not continue without a hormonal workup
  • Never mix peptides in the same vial
  • Hormone-dependent tumor, pregnancy: contraindication

VIYour journey in 3 steps

Step 1 · Consultation
Hormonal workup

Complete workup, contraindications, objectives, individualized protocol provided.

Step 2 · Treatment
Injections & monitoring

Injections according to the protocol, close hormonal monitoring.

Step 3 · Reassessment
Adjustment

Review of the workup, decision to continue or stop.

VIISide effects & level of evidence

Level of evidenceLimited human dataSmall human series or open-label trials; limited sample sizes and heterogeneous results.
Reported adverse effects
  • Vasomotor flushing
  • Headache
  • Nausea
  • Injection-site reaction
  • Transient LH / testosterone shift
Contraindications & precautions
  • Pregnancy, breastfeeding
  • Known or suspected hormone-dependent tumour
  • Children and adolescents (pubertal axis)
  • Hypersensitivity

Non-exhaustive list based on the available literature and known class effects; it replaces neither a product label nor an individual medical assessment.

VIIIPublications & references